EU PROJECTBringing an innovative pocket-sized 12-lead ECG with AI-automated interpretation to the market: AnyECG project. CLINICAL STUDYCardiolyse Risk of Heart Disorders score predicts heart failure outcomes in the MyoVasc study DEVICE INTEGRATIONCardiolyse and MedicubeX deepen their collaboration CLINICAL PILOTPost-ablation telemonitoring with GVM Care & Research at Maria Cecilia Hospital HOSPITAL PILOTCardiolyse improves cardiovascular care at Oxford University Hospitals EU PROJECTCRANE: pre-commercial procurement for remote chronic care

Heart Risks & HRV Analytics

Heart scores and HRV metrics from the same ECG signal.

No extra recording and no extra hardware. From the ECG you already capture, Cardiolyse derives more than 30 heart rate variability metrics, ECG codes and scores — from autonomic balance and stress to Heart Biological Age.

A woman taking a short single-lead ECG recording with a handheld device at a desk.
One ECG · 30+ metrics and scores
0+
HRV metrics, ECG codes and scores
1 signal
The same ECG / PPG signal used for the standard read
30–180 sec
Recording for the HRV-based scores
Validated
Risk of Heart Disorders Score
Cardiolyse scores

Scores that read beyond the routine ECG

Each score is calculated from the same ECG signal as the rhythm and interval analysis, using a short recording window.

Independent clinical validation

Risk of SCD / Risk of Heart Disorders (RoHD)

A score for the risk of sudden cardiac death and adverse cardiac outcomes, derived from a short single-lead ECG.

Fatigue Score

An HRV-based indicator of physiological fatigue. Its trend over time points towards chronic fatigue.

Emotional Score

An HRV-based indicator of emotional balance between sympathetic and parasympathetic activity.

Stamina

An HRV-based indicator of autonomic reserve and cardiovascular fitness.

Stress Level

An indicator of acute autonomic stress, based on the Baevsky Stress Index.

Heart Biological Age

An HRV-based estimate of cardiovascular age compared with chronological age.

Evidence base

Built on published methodology.

We state what evidence exists for each score today. Cardiolyse-branded validation of the HRV-based scores continues as further studies conclude.

Independent clinical validation

Cardiolyse Risk of Heart Disorders score predicts heart failure outcomes in the MyoVasc study

In the MyoVasc study at the University Medical Center Mainz (953 participants, 522 with symptomatic heart failure), the RoHD score predicted worsening of heart failure and all-cause death, independently of NT-proBNP and the MAGGIC risk score.

Read about the study →
Published outcome evidence

HRV linked to outcomes in heart failure

In the UK-HEART study of 433 patients with chronic heart failure, reduced SDNN — one of the HRV measures behind the Cardiolyse scores — independently predicted all-cause mortality and was the strongest independent predictor of death from progressive heart failure.

Read the study →
Established HRV science

Standard HRV methods underneath

Fatigue, Emotional, Stamina, Stress Level and Heart Biological Age build on established HRV measures and methods, such as the Baevsky Stress Index and the Samn–Perelli fatigue scale.

How it works

One recording. Two layers of insight.

  1. 01

    Record

    Capture an ECG / PPG — a short single-lead recording is enough. HRV-based scores use a 30–180-second window.

  2. 02

    Upload

    Send the signal through the REST API or a partner integration.

  3. 03

    Analyse

    HRV metrics, ECG codes and scores are calculated from the same signal as the standard ECG analysis.

  4. 04

    Results

    Values return as structured data, ready to show in your platform and to track over time.

Where it helps

More value from every ECG you record.

Screening & prevention

Cardiovascular screening programmes

Add risk and HRV scores to screening ECGs to help identify people who need a closer look.

Wellbeing & occupational health

Stress, fatigue and recovery tracking

Follow stress, fatigue and stamina trends in employees, athletes and other high-demand roles.

Platforms & research

Digital health products and studies

Offer HRV analytics in your own device or app through one API, or use the metrics as study endpoints.

Frequently asked

Heart risks and HRV analytics, answered.

Do the scores need a separate recording?

No. Scores and HRV metrics are calculated from the same ECG signal used for the standard analysis. RoHD uses a 30-second window; the HRV-based scores use a 180-second window.

Does it work with single-lead ECGs?

Yes. The scores and HRV metrics are designed to work from a short single-lead ECG, so they suit handheld devices, patches and wearables as well as standard ECG recorders.

Which metrics are included?

More than 30 in total: 21 HRV metrics (such as SDNN, RMSSD, pNN50, LF/HF, Stress index and DFA), five ECG codes (aVR lead, I lead, Froelicher and Aldrich anterior and inferior) and six scores, including RoHD and Heart Biological Age.

How well are the scores validated?

RoHD has independent clinical validation from the MyoVasc study. The score system follows a peer-reviewed methodology, and the HRV-based scores build on established HRV methods, with Cardiolyse-branded validation continuing.

Are the scores a diagnosis?

No. Scores are indicators that support a qualified healthcare professional’s assessment and are not a diagnosis on their own.

Can we test it on our own ECGs?

Yes. Send us a small set of anonymised recordings and we will walk you through the results. Contact us to set it up.

For everything else, see the full FAQ.

See what else your ECGs can tell you.

Send us a few anonymised recordings — we will return the HRV metrics and scores and review them with you.